Isaiah 5:20

"Woe to those who call evil good and good evil, who put darkness for light and light for darkness, who put bitter for sweet and sweet for bitter." NIV translation

In the previous passage the woe was for those who try to mix a little bit of God with a little bit of sin. In this verse, the woe is for those who completely abandon God's word and do not even acknowledge the sin. They are rebellious and trust in their own wisdom which is foolishness when compared to the wisdom of God.

Isaiah 5:21

"Woe to those who are wise in their own eyes and clever in their own sight." NIV translation

This woe is for those who think they know it all. We all know of people like this who think they are so smart. In this case it is talking about how men have turned away from the teachings of God and thought that their ways were superior. We are told that all wisdom comes from God and when men forget that and become proud of what they know, they will be humbled. We need to remember that "We see pieces, God sees the whole plan!"

Isaiah 5:22

"Woe to those who are heroes at drinking wine and champions at mixing drinks," NIV translation

This may seem odd for this part of the Bible but some people back in those days probably had a problem with alcohol. Today, the concept of "heroes at drinking wine" is probably easier to understand as we have all seen the drinking games and parties that occur at colleges and even at high schools. Isaiah tells the people here that they will suffer the consequences. For modern examples of this, you can check out the testimonies Saved From Suicide and Saved From Drugs And Alcohol.

Isaiah 5:23

"who acquit the guilty for a bribe, but deny justice to the innocent." NIV translation

The next woe is for those who are corrupt in their judgments. As long as men have been in positions of power, there have been corrupt men but this verse can remind us that God will take care of them.